The SPTLC2 Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to SPTLC2. This antibody recognizes Human, Mouse, and Rat antigen. The SPTLC2 Polyclonal Antibody has been validated for the following applications: Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011]